Monoclonal Anti-Plakoglobin (Catenin γ) antibody produced in mouse

半岛bd体育手机客户端 说明

一般描述

Plakoglobin is a desmosomal protein that regulates developmental signalling in vertebrates. Tyrosine phosphorylation of plakoglobin has been linked to adenocarcinomas . Plakoglobin may function as a tumor suppressor in ovarian and breast cancers .

特异性

The antibody recognizes the plakoglobin (catenin-γ) molecule (85 kDa and possibly a slightly lower band) by immunoblotting. It does not cross-react with β-catenin. The antibody reacts with plakoglobin in bovines, humans and dogs, but does not react with β catenin.

免疫原

recombinant chicken plakoglobin.

应用

Monoclonal anti-plakoglobin (catenin γ) antibody is suitable for use in immunocytochemistry (using MDCK cells), immunoprecipitation, and in immunoblotting . The antibody may also be used for immunohistochemistry (frozen sections), microarray, western blot (1:500, using cultured MDBK cells) and indirect immunofluorescence (1:1000, using cultured MDBK cells).

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD00164716
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	200
生物来源	mouse
偶联物	unconjugated
抗体形式	ascites fluid
antibody product type	primary antibodies
克隆	15F11, monoclonal
形式	buffered aqueous solution
分子量	antigen 85 kDa
包含	15 mM sodium azide
species reactivity	canine, bovine, human
technique(s)	immunocytochemistry: suitable using cultured cells immunohistochemistry (frozen sections): suitable immunoprecipitation (IP): suitable indirect immunofluorescence: 1:1,000 using cultured MDBK cells microarray: suitable western blot: 1:2,000 using cultured MDBK cells
同位素/亚型	IgG1
UniProt登记号	P14923
运输	dry ice
储存温度	?20℃
Gene Information	human ... JUP(3728)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	nwg
闪点(F)	Not applicable
闪点(C)	Not applicable