半岛bd体育手机客户端 说明
一般描述
Riboflavin binding protein (RBP) transports riboflavin through the bloodstream of the laying hen into the eggs, where the vitamin is essential for embryonic growth and development. RBP consists of a single polypeptide chain containing 9 disulfide bonds. It is a glycoprotein containing ~14% carbohydrate, with sugar moieties including galactose, mannose and glucosamine, and is phosphorylated.
Riboflavin Binding Protein (RBP) comprises of 19 cysteines and corresponds to a molecular weight of 30 kDa. Egg white RBP is produced in the oviduct cells. Chicken egg white RBP contains an N-terminal ligand binding domain and a C-terminal phosphorylated motif.
应用
Riboflavin Binding Protein from chicken egg white may be used in fluorescence quenching experiments.
包装
2, 10 mg in glass bottle
生化/生理作用
Riboflavin binding protein binds to flavokinase and regulates its activity.
Riboflavin Binding Protein (RBP) is crucial for normal embryo development. RBP interacts with riboflavin and its analogs. The RBP-riboflavin complex is stabilized by interaction between the isoalloxazyne ring of riboflavin and the tyrosine 75 and tryptophan 156 of residues of RBP. RBP elicits sweet supressing functionality and may interact with the sweet taste receptor.
制备说明
Supplied as the riboflavin-depleted apo-form.
基本信息
NACRES | NA.26 |
半岛bd体育手机客户端 性质
生物来源 | chicken egg white |
质量水平 | 200 |
测定 | ≥50% protein basis (biuret) |
形式 | lyophilized powder |
UniProt登记号 | P02752 |
储存温度 | ?20℃ |
Gene Information | chicken ... RBP(396449) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich