半岛bd体育手机客户端 说明

一般描述

Interleukin-1α (IL-1α) is a cytokine that belongs to the interleukin-1 (IL-1) family. It is located intracellularly in hematopoietic and non-hematopoietic cells. IL-1α gene is located on the human chromosome at 2q14.1.

应用

Interleukin-1α (IL-1α) has been used:

• to study its effects on human colorectal adenocarcinoma cells
• to stimulate primary human fetal retinal pigment epithelium (hfRPE) cells
• to pre-stimulate human THP-1 monocytes

包装

2 μg in serum bottle

生化/生理作用

Interleukin-1α (IL-1α) plays a crucial role in inflammation during cell necrosis. It also regulates the recruitment of interleukin-1β (IL-1β), neutrophils, chemokines, and other cytokines at the site of injury. IL-1α exhibits a dual function of binding to its cell surface receptor as well as chromatin.

外形

Lyophilized from 0.2 μm filtered 10 mM sodium phosphate , pH 8.0, plus 50 mm NaCl and 50 μg bovine serum albumin (BSA) per μg cytokine.

分析说明

The proliferative activity of human IL-1α is tested in culture using the murine cell line D10S.

基本信息

MDL编号	MFCD00164814
NACRES	NA.77

半岛bd体育手机客户端 性质

质量水平	100
生物来源	human
重组	expressed inE. coli
测定	≥98% (SDS-PAGE and HPLC)
形式	lyophilized powder
质量	endotoxin tested
分子量	~17 kDa
包装	pkg of 2 and 10 μg
technique(s)	cell culture | mammalian: suitable
UniProt登记号	P01583
储存温度	?20℃
Gene Information	human ... IL1A(3552)

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P261 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves