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Anti-TRPC1 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
T8276
规格纯度
affinity isolated antibody, lyophilized powder
价格
3583.81 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-TRPC1 antibody produced in rabbit
Trpc1 Antibody
Anti-Transient receptor potential cation channel, subfamily C, member 1
Trpc1 Antibody-Anti-TRPC1 antibody produced in rabbit
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Transient receptor potential cation channel subfamily C member 1 (TRPC1) is encoded by the gene mapped to human chromosome 3q22-24. The encoded protein is a member of the transient receptor potential (TRP) superfamily of cation channels and is distributed in both glomeruli and glomerular mesangial cells.

免疫原

Synthetic protein corresponding to amino acids 557-571 of human TRPC1 (GenBank?Accession No. P48995). The epitope is identical in mouse and rat and highly homologous in bovine andXenopus.

生化/生理作用

Transient receptor potential cation channel subfamily C member 1 (TRPC1) facilitates Ca2+entry upon store depletion in a variety of cell types by forming a multimeric complex with other TRPCs. The encoded protein is implicated in the odontoblast-like differentiation of human dental pulp cells (hDPCs). Mutation in the gene is associated with the development type 2 diabetes mellitus (T2D). Decreased expression of the gene leads to hepatocellular carcinoma cell proliferation and thus, TRPC1 can be considered as a potential therapeutic target for hepatocellular carcinoma.

外形

Lyophilized at 0.3 mg/ml from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.05% sodium azide.

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号 MFCD02686004
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 lyophilized powder
species reactivity rat
technique(s) immunohistochemistry: suitable
western blot (chemiluminescent): suitable
UniProt登记号 Q9QX01
储存温度 ?20℃
Gene Information human ... TRPC1(7220)
mouse ... Trpc1(22063)
rat ... Trpc1(89821)

安全信息

象形图 GHS06GHS09
警示用语: Danger
危险声明 H301 + H311 - H411
预防措施声明 P273 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P391 - P501
危险分类 Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Aquatic Chronic 2
补充剂危害 EUH032
储存分类代码 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Sigma-Aldrich

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