Monoclonal Anti-ARNO (Cytohesin-2) antibody produced in mouse

半岛bd体育手机客户端 说明

一般描述

ARNO (Cytohesin-2) is a guanine-nucleotide exchange factor that belongs to Arf family of GTP-associated proteins. ARNO has been shown to modulate the movement of mouse preadipocyte 3T3-L1 cells. Studies have reported that cytohesin-2 is overexpressed in pulmonary cancers and can also serve as biomarker of prognosis in hepatocellular carcinomas.
Monoclonal Anti-ARNO (Cytohesin-2) reacts specifically with ARNO, and does not cross-react with other members of the cytohesin family. The antibody associates with human and rat ARNO.

免疫原

recombinant, human ARNO (ARFnucleotide-binding-site opener).

应用

To determine if ARNO binds to phosphoinositides, a protein-overlay assay was performed using monoclonal mouse anti-ARNO as the primary antibody for ARNO detection on membranes spotted with phosphoinositides and incubated with ARNO.
Mouse monoclonal anti-ARNO (Cytohesin-2) antibody can be used for western blot (5-10μg/mL using a whole extract of rat brain), microarray, indirect ELISA and immunocytochemistry applications.

外形

0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD03454755
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	200
生物来源	mouse
偶联物	unconjugated
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	CYT2-21, monoclonal
形式	buffered aqueous solution
分子量	antigen 40 kDa
species reactivity	rat, human
浓度	~2 mg/mL
technique(s)	immunocytochemistry: suitable indirect ELISA: suitable microarray: suitable western blot: 5-10 μg/mL using a whole extract of rat brain
同位素/亚型	IgG1
UniProt登记号	Q99418
储存温度	?20℃
Gene Information	human ... CYTH2(9266) rat ... Cyth2(116692)