Anti-Rat IgG (H+L), highly cross adsorbed antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

IgG (immunoglobulin G) consists of four subclasses: IgG1, IgG2, IgG3 and IgG4. The IgG structure possesses four polypeptide chains containing two identical γ heavy (H) chains and two identical κ or λ light (L) chains of 50kDa and 25kDa respectively. The chains are interlinked with a disulfide bond. Both the L and the H chains consist of a variable domain at the N-terminal. The C-terminal bears′ constant domains: three in H chain with a hinge region and one in the L chain. IgG antibody is enriched in mother′s milk. IgG contributes to 10?20% of plasma protein and is regarded as one of the most abundant serum protein.

特异性

This product was prepared from monospecific antiserum by immunoaffinity chromatography using Rat IgG coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Rabbit Serum, Rat IgG and Rat Serum. No reaction was observed against Human Serum Proteins.

免疫原

Rat IgG whole molecule

生化/生理作用

IgG (immunoglobulin G) antibody protects against bacterial, fungal and viral infections. IgG antibody has its function similar to IgM antibody in complement system activation. IgG participates in hypersensitivity type II and type III. It helps in opsonization, complement fixation and antibody-dependent cell-mediated cytotoxicity. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

物理属性

Antibody format: IgG

外形

Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.46

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	secondary antibodies
克隆	polyclonal
形式	buffered aqueous solution
species reactivity	rat
浓度	1.97 mg/mL
technique(s)	immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable
运输	wet ice
储存温度	2-8℃

安全信息

储存分类代码	12 - Non Combustible Liquids
闪点(F)	Not applicable
闪点(C)	Not applicable