Anti-Human Hemoglobin antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

HBB (hemoglobin subunit β) codes for a β globin that consists of three exons. This gene is located on human chromosome 11p15. HBB is a serum protein that belongs to the histone-like protein family.

免疫原

Hemoglobin isolated from normal adult human red blood cells and treated to remove lipoproteins.

应用

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Anti-Human Hemoglobin antibody produced in rabbit was used for immunoblotting using crude human cerebellar protein extracts and membrane extracts of human RBC. It was used for immunohistochemistry of human tongue cancer samples.
Anti-Human Hemoglobin antibody has been used in pulse chase experiments and western blotting.

生化/生理作用

Hemoglobin (Hb) is oxygen-binding metalloprotein that is present in the red blood cells. The most abundant Hb is HbA tetramer that is made up of two α, two β chains and the nonprotein heme group. The heme group contains iron ion and a porphyrin ring. Mutations in Hb gene result in hemoglobinopathies, the best known being sickle-cell disease and thalassemias.
HBB (hemoglobin subunit β) participates in oxygen transport from the lung to various peripheral tissues. Mutation in HBB result in Sickle cell disease (SCD). Overexpression of HBB has been observed in patients with periodontal disease.

制备说明

treated to remove lipoproteins

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号

MFCD00162411

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	200
偶联物	unconjugated
抗体形式	whole antiserum
antibody product type	primary antibodies
克隆	polyclonal
包含	15 mM sodium azide
species reactivity	human
technique(s)	indirect ELISA: 1:8,000
UniProt登记号	P68871
运输	dry ice
储存温度	?20℃
Gene Information	human ... HBB(3043)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable