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位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-CAMK2D antibody produced in mouse

Monoclonal Anti-CAMK2D antibody produced in mouse

品牌
Sigma-Aldrich
货号
WH0000817M2
规格纯度
clone 1A8, purified immunoglobulin, buffered aqueous solution
价格
4474.51 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Monoclonal Anti-CAMK2D antibody produced in mouse
Anti-MGC44911
Anti-calcium/calmodulin-dependent protein kinase (CaM kinase) II delta
Anti-CAMKD
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The gene encoding calcium/calmodulin dependent protein kinase IIδ (CAMK2D) is localized on human chromosome 4q26. The encoded protein is a member of serine/threonine protein kinase family and the Ca2+/calmodulin-dependent protein kinase subfamily.
The product of this gene belongs to the serine/threonine protein kinase family and to the Ca2+/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: α, β, γ, and δ. The product of this gene is a δ chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns

免疫原

CAMK2D (AAH32784, 301 a.a. ~ 410 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPI

生化/生理作用

As a subunit of the calcium/calmodulin dependent protein kinase II complex, calcium/calmodulin dependent protein kinase II complex δ (CAMK2D) modulates the functions of ion channels and Ca2+handling proteins. It also regulates the phosphorylation and acetylation of histones. CAMK2D has been shown to be overexpressed in the myocardium of diabetic patients.

外形

Solution in phosphate buffered saline, pH 7.4

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 1A8, monoclonal
形式 buffered aqueous solution
species reactivity mouse
technique(s) indirect ELISA: suitable
indirect immunofluorescence: suitable
western blot: 1-5 μg/mL
同位素/亚型 IgG2bλ
GenBank?accession no. BC032784
UniProt登记号 Q6PHZ2
运输 dry ice
储存温度 ?20℃
Gene Information human ... CAMK2D(817)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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