Microbial DNA standard fromBacillus subtilis

半岛bd体育手机客户端 说明

一般描述

Microbial DNA standard fromBacillus subtilis(B. subtilis) is a genomic DNA microbial standard that can serve as a standard for benchmarking the performance, along the workflow of microbiomics or meta-genomics analyses. It can also be used as a tool to increase reproducibility and allow comparison of results obtained by different labs. Standardization of sample analysis is currently needed in microbiome genomics research workflow. Lack of standardization can lead to biases and errors in common processes during sample preparation and analysis such as sample amplification, sequencing and bioinformatics analyses.Bacillus subtilisis a gram positive, aerobic bacterium, rod-shaped, endospore-forming, catalase-positive. It is traditionally considered as a soil microorganism.Bacillus subtilisis genetically well characterized and serves as a model organism for important gram-positive pathogens such asBacillus anthracis,Staphylococcus aureusetc.B. subtilispossess an extreme adaptation ability to various environmental stress conditions by modifying its motility, uptake of exogenous DNA, biofilm formation and sporulation. Recent studies have identified and characterizedB. subtilisisolates from human gastrointestinal track suggestingB. subtilisas a gut commensal. Moreover,B. subtilispresence in the gut was found to correlate with probiotic effects such as anti-diarrhea effect, anti-microbial effect, immune-stimulatory effect, competition with pathogens, normal flora growth stimulation and prevention of intestinal inflammation.B. subtilisbeneficial effect on gut inflammation may also suggest it as potential probiotic treatment for inflammatory bowel diseases (IBD), including Crohn′s and ulcerative colitis. In addition, it was demonstrated that a peptide produced byB. subtilispossess antiviral effect against influenza virus.

应用

Suitable for Quantitative standard for PCR, Sequencing and NGS

特点和优势

• Individual microbial standard for microbiomics and meta-genomics workflow
• Suitable standard for PCR, sequencing and NGS
• Improve Bioinformatics analyses
• Increases reproducibility
• Compare results lab to lab

外形

Liquid - The genomic DNA is provided at >=10 ng/μL concentration in TE buffer pH 8.0

其他说明

It is recommended to avoid freeze thaw cycles of this product.

半岛bd体育手机客户端 性质

形式	liquid
浓度	10 ng/μL
technique(s)	PCR: suitable
运输	ambient
储存温度	?20℃

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable