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位置: 首页> 品牌> Sigma-Aldrich> Anti-Collagen Type III antibody, Mouse monoclonal

Anti-Collagen Type III antibody, Mouse monoclonal

品牌
Sigma-Aldrich
货号
SAB4200749
规格纯度
clone FH-7A, purified from hybridoma cell culture
价格
6732.28 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-Collagen Type III antibody, Mouse monoclonal
Anti-COL3A1
Anti-Collagen alpha-1(III) chain
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Anti-collagen type III antibody, mouse monoclonal (mouse IgG1 isotype) is derived from the FH-7A hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c immunized mouse.
Monoclonal anti-collagen type III specifically recognizes native and denatured collagen type III from human 1 and rat 2 origin. It does not recognize collagen types I, II, IV, V, VI and X.
Collagen type III, also known as collagen α-1(III) (COL3A1), is encoded by the gene mapped to human chromosome 2q24.3-q31. It is the highly expressed collagen in blood vessels and hollow organs.

免疫原

Human Collagen Type III

生化/生理作用

Collagen a-1(III) (COL3A1) serves as a potent adjunct marker for both differentiating fibroadenoma (FA) from phyllodes tumor (PT) and measuring malignant potential in PTs. Overexpression of the gene in glomerular leads to the development of collagen type III glomerulopathy. Mutations in the gene is associated with the development of familial aortic aneurysms and Ehlers-Danlos syndrome.

外形

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

储存及稳定性

Store at -20℃. For continuous use, store at 2-8℃ for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

其他说明

In order to obtain best results in different techniques and preparations we recommend determining optimal working concentration by titration test.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 200
生物来源 mouse
抗体形式 purified from hybridoma cell culture
antibody product type primary antibodies
克隆 FH-7A, monoclonal
形式 buffered aqueous solution
分子量 ~70 kDa
species reactivity human, rat
浓度 ~1.0 mg/mL
technique(s) ELISA: suitable
immunoblotting: suitable
immunofluorescence: suitable
immunohistochemistry: 10-20 μg/mL using heat-retrieved formalin-fixed, paraffin-embedded rat skin sections.
同位素/亚型 IgG1
UniProt登记号 P02461
运输 dry ice
储存温度 ?20℃
Gene Information human ... COL3A1(1281)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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