Interferon-αA human

半岛bd体育手机客户端 说明

应用

Interferon-αA human has been used to:

• study the effect of Chikungunya virus on interferon-mediated JAK (Janus kinase)-STAT (signal transducers and activators of transcription) signaling
• study the effect of interferon-α and PRK2 (protein kinase C-related kinase 2) inhibitors on hepatitis C virus replication
• compare the effect ofMonascuspigment derivatives on hepatitis C virus replication

生化/生理作用

Cytokine with anti-viral, anti-proliferative, immunoregulatory, and proinflammatory activities. Type I Interferons are a closely related family of 165-172 amino acid proteins that are produced by leukocytes (α subtypes), fibroblasts (β subtypes), lymphocytes (ω subtypes) and ruminant embryos (τ subtypes). Interferon induces a variety of effects on target cells including antiviral, antiproliferative and immunomodulatory activities.

外形

Supplied as a solution in 5 mM sodium acetate, pH 4.0.

分析说明

The biological activity is determined in the cytopathic effect inhibition assay using MDBK cells with vesicular stomatitis virus (VSV). A cytopathic effect of 50% is produced with 1 unit/ml interferon. The units are determined with respect to WHO International standard reference for human interferonαA.

基本信息

MDL编号

MFCD01635115

半岛bd体育手机客户端 性质

质量水平	200
生物来源	human
重组	expressed inE. coli
测定	≥95%
形式	buffered aqueous solution
分子量	19 kDa
包装	pkg of 20 μg
浓度	≥0.2 mg/mL
technique(s)	cell culture | mammalian: suitable
杂质	endotoxin, tested
颜色	colorless
UniProt登记号	P01563
运输	wet ice
储存温度	?20℃
Gene Information	human ... IFNA2(3440)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves