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Anti-CFTR antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4501942
规格纯度
affinity isolated antibody
价格
5045.46 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-CFTR antibody produced in rabbit
Cystic fibrosis transmembrane conductance regulator
cAMP- dependent chloride channel
ABCC7
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Anti-CFTR Antibody detects endogenous levels of total CFTR protein.
CFTR (Cystic fibrosis transmembrane conductance regulator, ATP-binding cassette sub-family C, member 7) is a membrane-associated, N-linked glycoprotein.

免疫原

The antiserum was produced against synthesized peptide derived from human CFTR.
Immunogen Range:711-760

应用

Anti-CFTR antibody produced in rabbit is suitable for immunohistochemistry and western blot applications.

生化/生理作用

CFTR (Cystic fibrosis transmembrane conductance regulator, ATP-binding cassette sub-family C, member 7) is mainly involved in the regulation of Na+and Cl-transport by acting as a linear, cAMP activated, chloride channel. In addition, it is also associated with different transport signaling pathways. It has been reported that CFTR controls functionality of outwardly rectifying Cl-channels (ORCCs) by facilitating the transport and delivery of potent autacoid agonist and ORCC regulator ATP. It has also been suggested that CFTR can interact with Na+-reabsorptive pathway. CFTR is associated with congenital bilateral absence of the vas deferens (CBAVD) and causes the genital form of cystic fibrosis (CF). The CFTR gene may also responsible for male infertility. It may be useful for assisting reproduction technology.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号 MFCD01321917
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen 168 kDa
species reactivity rat, mouse, human
浓度 ~1 mg/mL
technique(s) ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号 P13569
UniProt登记号 P13569
运输 wet ice
储存温度 ?20℃
Gene Information human ... CFTR(1080)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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