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位置: 首页> 品牌> Sigma-Aldrich> Anti-Serotonin Transporter (N-terminal) antibody produced in rabbit

Anti-Serotonin Transporter (N-terminal) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4200039
规格纯度
~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution
价格
5045.46 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-Serotonin Transporter (N-terminal) antibody produced in rabbit
Anti-SLC6A4 solute carrier family 6, member 4
Anti-5HTT
Anti-5-hydroxytryptamine transporter
Anti-HTT
Anti-OCD1
Anti-SERT
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Solute carrier family 6 member 4 (SLC6A4), also known as 5-hydroxytryptamine transporter (5-HTT), is an integral membrane protein, encoded by the gene mapped to human chromosome 17q11.2. The encoded protein is a member of SLC6 gene family and is mainly expressed in brain and blood cells.

应用

Anti-Serotonin Transporter (N-terminal) antibody produced in rabbit has been used in western blot analysisand immunohistochemistry.

生化/生理作用

Solute carrier family 6 member 4 (SLC6A4) catalyzes the transport of neurotransmitter serotonin from the synaptic space into presynaptic neurons. It also plays a vital role in mood and anxiety regulation. Mutation on the gene might alter the expression of serotonin (5HT) in the synaptic cleft, which ultimately leads to schizophrenia. Allelic variations in the gene increases the risk of susceptibility to autism and rigid-compulsive behaviors.
The polymorphic promoter region of the serotonin transporter gene serotonin-transporter-linked polymorphic region (5HTTLPR), has been suggested to affect serotonin uptake and may play a role in the pathogenesis of depression, obsessive-compulsive disorder (OCD) and aggressive behavior.

外形

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 200
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen ~83 kDa
species reactivity human
浓度 ~1.5 mg/mL
technique(s) western blot: 1.5-3.0 μg/mL using SH-SY5Y cell lysates
UniProt登记号 P31645
运输 dry ice
储存温度 ?20℃
Gene Information rat ... Slc6a4(25553)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable

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