Anti-Dystrophin antibody, Mouse monoclonal

半岛bd体育手机客户端 说明

一般描述

Dystrophin is a rod-shaped cytoskeletal protein located to the periphery (plasma membrane) of normal striated muscle fibers.
Anti-Dystrophin antibody, Mouse monoclonal (mouse IgG2b isotype) is derived from the MANDYS8 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from mouse immunized with fragment of recombinant human dystrophin. Dystrophin is a 427 kD protein which joins the actin cytoskeleton to laminin. It possesses multiple domains and is localized to the extracellular matrix. Dystrophin contains NH2-terminal domain for actin binding. The C-terminal domain interacts with dystrophin associated protein (DAP).

特异性

Anti-Dystrophin antibody, Mouse monoclonal specifically recognizes an epitope located on the rod domain of the human dystrophin molecule.

免疫原

recombinant human dystrophin

应用

Anti-Dystrophin antibody, Mouse monoclonal has been used in immunoblotting and immunohistochemistry.

生化/生理作用

Dystrophin is known to prevent muscle fibre injury due to contraction.

外形

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as preservative.

其他说明

This product is for R&D use only, not for drug, household, or other uses.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

质量水平	200
生物来源	mouse
抗体形式	purified from hybridoma cell culture
antibody product type	primary antibodies
克隆	MANDYS8, monoclonal
形式	buffered aqueous solution
分子量	~427 kDa
species reactivity	human, mouse, porcine, rabbit, rat
浓度	~1.0 mg/mL
technique(s)	immunoblotting: suitable immunohistochemistry: 5-10 μg/mL using acetone fixed rat tongue frozen sections
同位素/亚型	IgG2b
UniProt登记号	P11532
运输	dry ice
储存温度	?20℃

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable