Anti-α-2-Macroglobulin antibody produced in chicken

半岛bd体育手机客户端 说明

免疫原

α-2-Macroglobulin (validated) native human protein.
Immunogen Sequence: GI # 68765, sequence 1-1474

应用

Anti-α-2-Macroglobulin antibody produced in chicken is suitable for western blotting at a working dilution of 1:500 and for cell staining at a working dilution of 1:200. It is also used for indirect ELISA.

生化/生理作用

A2M (α-2-macroglobulin) inhibits all four classes of proteinases by a unique ′trapping′ mechanism. This protein undergoes a conformational change when a proteinase binds and cleaves a specific peptide stretch called the "bait region" in the protein. This modified protein traps the bound proteinase It is involved in the clearance and degradation of Aβ, which is a major component of beta-amyloid deposits. Therefore, it is associated with Alzheimer′s disease (AD).

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD00162122
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	chicken
质量水平	200
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
species reactivity	human, rat, mouse
manufacturer/tradename	Genway 15-288-20008F
technique(s)	indirect ELISA: suitable western blot: suitable
NCBI登记号	MAHU
UniProt登记号	P01023
运输	wet ice
储存温度	?20℃
Gene Information	human ... A2M(2)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)