Anti-Mouse IgG (whole molecule)-Agarose antibody produced in goat

半岛bd体育手机客户端 说明

一般描述

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It mainly helps in immune defense. It is a glycoprotein. IgG is a major class of immunoglobulin. Mice consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE.
Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases. Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice. Goat Anti-Mouse IgG (whole molecule)-Agarose antibodies bind to all mouse IgG subclasses.

免疫原

IgG isolated from pooled normal mouse serum

应用

Soluble antigens from meningococci extracts were mixed with ascitic fluid containing primary antibody and 50 μl of agarose-linked goat anti-mouse IgG for 5 hours at 4 ℃.
Goat Anti-Mouse IgG (whole molecule)-Agarose antibodies have been used for immunoprecipiation assays. The product can also be used for Ouchterlony double diffusion applications.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Chromatin immunoprecipitation (1 paper)
Immunoprecipitation (1 paper)

包装

2, 5, 25 mL in glass bottle

生化/生理作用

IgG helps in opsonization, complement fixation and antibody-dependent cell-mediated cytotoxicity. Immunoglobulin G (IgG) participates in hypersensitivity type II and type III. IgG2a of IgG has cytotropic properties and IgG2 molecules have the ability to activate complement.

外形

Suspension in 0.5 M NaCl containing preservative

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD03791275
NACRES	NA.46

半岛bd体育手机客户端 性质

质量水平	200
生物来源	goat
偶联物	agarose conjugate
抗体形式	affinity isolated antibody
antibody product type	secondary antibodies
克隆	polyclonal
形式	suspension
species reactivity	mouse
标记范围	≥5 mg per mL
technique(s)	Ouchterlony double diffusion: suitable immunoprecipitation (IP): suitable
基质	Cross-linked 4% beaded agarose
基质活化	cyanogen bromide
基质隔离区	1 atom
容量	0.4 mg/mL, resin binding capacity (mouse IgG)
储存温度	2-8℃

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 3