Leupeptin, Hemisulfate, Microbial-CAS 103476-89-7-Calbiochem

半岛bd体育手机客户端 说明

一般描述

A reversible inhibitor of trypsin-like proteases and cysteine proteases. Also known to inhibit activation-induced programmed cell death and to restore defective immune responses of HIV⁺donors. Also available as a 50 mM solution in H₂O (Cat. No. 509281).
A reversible inhibitor of trypsin-like proteases and cysteine proteases. Also known to inhibit activation-induced programmed cell death and to restore defective immune response in HIV⁺donors. Often used for the inhibition of endoproteinase Lys-C, kallikrein, papain, plasmin, thrombin, cathepsin B, and trypsin. Leupeptin does not inhibit chymotrypsin, elastase, renin, or pepsin. The recommended working range is 10-100 ?M for most applications.

包装

50 mg in Glass bottle
100 mg in Plastic ampoule
5, 10, 25 mg in Plastic ampoule

生化/生理作用

Product does not compete with ATP.
Primary Target
trypsin- and cysteine-like proteases
Reversible: yes
Cell permeable: no

警告

Toxicity: Standard Handling (A)

序列

Ac-Leu-Leu-arginal, hemisulfate

重悬

Following reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Aqueous stock solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.

其他说明

Montenez, J.P., et al. 1994.Toxicol. Lett.73,201.
Sarin, A., et al. 1994.J. Immunol.153,862.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C20H38N6O4· 0.5H2SO4
分子量	475.59
MDL编号	MFCD00037012

半岛bd体育手机客户端 性质

质量水平	200
测定	≥90% (HPLC)
形式	lyophilized solid
manufacturer/tradename	Calbiochem?
储存条件	OK to freeze desiccated (hygroscopic)
颜色	white
溶解性	water: 50 mg/mL
运输	ambient
储存温度	?20℃
InChI	1S/C20H38N6O4/c1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22/h11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23)/p+1/t15-,16-,17-/m0/s1
InChI key	GDBQQVLCIARPGH-ULQDDVLXSA-O

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable