半岛bd体育手机客户端 说明
应用
Air- and moisture-tolerant, this (-)-PSI Reagent was developed in the Baran lab for stereocontrolled synthesis of phosphorothioate oligonucleotides. The enantiomer, (+)-PSI Reagent, is also available (cat# ALD00604).
The PSI Reagents open access to thiophosphate-based nucleotide molecules with therapeutic promise as demonstrated by the Baran lab in the preparation of pure stereoisomers of cyclic dinucleotides (CDNs) and antisense oligonucleotides (ASOs).
其他说明
Unlocking P(V): Reagents for chiral phosphorothioate synthesis
PSI on OpenFlask
法律信息
PCT/US2019/027256; U.S. Nonprovisional Patent Application #16/382,692
基本信息
经验(实验)分子式 | C16H16F5OPS3 |
分子量 | 446.46 |
半岛bd体育手机客户端 性质
测定 | 95% |
形式 | powder or crystals |
mp | 103-107 ℃ |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich