半岛bd体育手机客户端 说明
一般描述
Extremely potent and selective irreversible inhibitor of thrombin (Kobs/[I] = 107M-1S-1). Reacts with thrombin in a 1:1 stoichiometry. Can also be used to inhibit tissue plasminogen activator. Factor VIIa, and Factor XIa.
Extremely potent and selective irreversible inhibitor of thrombin (Kobs/[I] = 107M-1S-1). Reacts with thrombin in a 1:1 stoichiometry. Can also be used to inhibit tissue plasminogen activator, Factor VIIa, and Factor XIa. Also available as a 25 mM solution in H2O (Cat. No. 508773).
包装
5, 25 mg in Plastic ampoule
Packaged under inert gas
生化/生理作用
Product does not compete with ATP.
Primary Target
Thrombin
Reversible: no
Kobs/[I] = 107 M?? sec?? as inhibitor of thrombin
Cell permeable: no
警告
Toxicity: Standard Handling (A)
序列
H-D-Phe-Pro-Arg-chloromethylketone, 2HCl
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions (pH <4) are stable for up to 4 months at -20°C. Rapidly decomposes at an alkaline pH.
其他说明
Rosado, J. A., et al. 2002.J. Biol. Chem.277,42157.
Odake S., et al. 1995.J. Enzyme Inhib.9,17.
Arni, R.K., et al. 1993.Biochemistry32,4727.
Yamashita, T., et al. 1993.Thromb. Res.69,93.
Schmaier, A.H., et al. 1992.Thromb. Res.67,479.
Collen, D., et al. 1982.J. Lab. Clin. Med.99,76.
Kettner, C., and Shaw, E. 1981.Methods Enzymol.80,826.
Kettner, C., and Shaw, E. 1979.Thromb. Res.14,969.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C21H33Cl3N6O3 |
| 分子量 | 523.88 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥80% (HPLC) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem? |
| 储存条件 | OK to freeze desiccated protect from light |
| 颜色 | white |
| 溶解性 | water: 100 mg/mL |
| 运输 | ambient |
| 储存温度 | 2-8℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
