半岛bd体育手机客户端 说明
应用
Tyrphostin AG 825 has been used to study its effects on iodide uptake in EMT6 cells1.
生化/生理作用
Tyrphostin AG 825 has been used in combination with hypericin-mediated photodynamic therapy (HY-PDT) for evaluating its therapeutic effects in HER2 overexpressing human breast cancer cells. This study reported that AG 825 combination increased the induction of cell death, HER2 degradation and inhibited colony formation in cancer cells2.
EGF receptor tyrosine kinase inhibitor, inactive against IGF-1 Receptor.
特点和优势
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制备说明
Tyrphostin AG 825 is soluble in DMSO and methanol.
基本信息
| 经验(实验)分子式 | C19H15N3O3S2 |
| 分子量 | 397.47 |
| MDL编号 | MFCD01074971 |
| PubChem化学物质编号 | 329826823 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 200 |
| 测定 | ≥92.5% |
| 形式 | powder |
| 溶解性 | DMSO: soluble methanol: soluble |
| 储存温度 | ?20℃ |
| SMILES string | COc1cc(cc(CSc2nc3ccccc3s2)c1O)\C=C(/C#N)C(N)=O |
| InChI | 1S/C19H15N3O3S2/c1-25-15-8-11(6-12(9-20)18(21)24)7-13(17(15)23)10-26-19-22-14-4-2-3-5-16(14)27-19/h2-8,23H,10H2,1H3,(H2,21,24)/b12-6+ |
| InChI key | KXDONFLNGBQLTN-WUXMJOGZSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
