半岛bd体育手机客户端 说明
应用
Acylase I from porcine kidney has been used to study the acylase I-catalyzed deacetylation of various S-alkyl-N-acetyl-L-cysteines and their carbon and oxygen analogues . Acylase I may be useful to catalyze N-acetyl amino acids to enantiomerically pure L-amino acids .
包装
1, 10 g in poly bottle
生化/生理作用
Acylase I is a zinc metalloprotein that catalyzes the kinetic resolution of unnatural and rarely occurring α-amino acids. Its enantioselectivity for the hydrolysis of N-acyl L-α-amino acids is nearly absolute, yet it accepts substrates having a wide range of structure and functionality. Acylase I catalyzes the deacetylation of N-acetyl-L-cysteine and S-alkyl-N-acetyl-L-cysteines. n-Butylmalonic acid is an inhibitor of acylase I. S-alkyl-N-acetyl-L-cysteines with short (C0-C3) and unbranched S-alkyl substituents have been found to be good acylase I substrates.
单位定义
One unit will hydrolyze 1.0 μmole of N-acetyl-
分析说明
Protein determined by biuret.
基本信息
酶学委员会(EC)编号 | 3.5.1.14 ( BRENDA | IUBMB ) |
EC 号 | 232-732-3 |
MDL编号 | MFCD00081285 |
NACRES | NA.54 |
半岛bd体育手机客户端 性质
质量水平 | 200 |
类型 | Grade II |
形式 | salt-free, lyophilized powder |
specific activity | 500-1,500 units/mg protein |
UniProt登记号 | P37111 |
储存温度 | ?20℃ |
Gene Information | pig ... ACY1(396930) |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H315 - H319 - H334 - H335 |
预防措施声明 | P302 + P352 - P305 + P351 + P338 |
危险分类 | Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3 |
靶器官 | Respiratory system |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich