半岛bd体育手机客户端 说明

应用

次黄嘌呤是一种营养添加剂，适用于细菌、寄生虫(恶性疟原虫)和动物细胞等多种细胞培养应用。 次黄嘌呤是杂交瘤技术所用选择培养基的组分。
Hypoxanthine has been used:

• to gavage mice and to evaluate the activity of xanthine oxidase (XO) in pasteurized whole milkin vivoin potassium oxonate (PO) -induced mouse model of hyperuricemia
• as a supplement in Iscove′s modified Dulbecco′s medium (IMDM) medium to cultivatein-vitrocell line (EL-1 cells)
• as a pure standard for the quantification of hypoxanthine in vitreous fluid sample using high-performance liquid chromatography-ultra-violet (HPLC-UV) for the estimation of post-mortem interval

包装

1, 5, 25, 100 g in poly bottle

生化/生理作用

Hypoxanthine acts as an intermediate in purine metabolism. It elicits a vital role as a 5′-base of the anticodon in a few transfer-RNAs. Though similar to guanine (Gua), it is devoid of the exocyclic amino group at C(2) position. It may be used as a substrate to study the specificity and kinetics of hypoxanthine-guanine phosphoribosyl transferases.

基本信息

经验(实验)分子式	C5H4N4O
分子量	136.11
Beilstein	5811
EC 号	200-697-3
MDL编号	MFCD00005725
PubChem化学物质编号	24895850
NACRES	NA.51

半岛bd体育手机客户端 性质

质量水平	300 200
生物来源	synthetic (organic)
测定	≥99.0%
形式	powder
mp	>300 ℃ (lit.)
溶解性	formic acid: water (2:1): 50 mg/mL, clear to slightly hazy, colorless to yellow
SMILES string	O=C1NC=Nc2nc[nH]c12
InChI	1S/C5H4N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)
InChI key	FDGQSTZJBFJUBT-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)