N⁶-Benzoyladenine

半岛bd体育手机客户端 说明

应用

N6-Benzoyladenine is used in the organic synthesis of adenine derivative molecules such as bicyclic adenine nucleoside via a condensation reaction between L-threo-pentofuranose derivative 1 and 6-N-benzoyladenine and to produce oxy-peptide nucleic acids.

包装

5, 25 g in poly bottle

生化/生理作用

N⁶-Benzoyladenine comprises of adenine moiety and is a potent inhibitor of bromodomain-containing protein 4 (BRD4). N⁶-Benzoyladenine modulates tumor necrosis factor α (TNF-α) levels. It elicits cytotoxicity in liver and ileum cancer cells and may serve as a potential candidate agent for cancer chemotherapy.

基本信息

经验(实验)分子式	C12H9N5O
分子量	239.23
MDL编号	MFCD00037927
PubChem化学物质编号	24891827
NACRES	NA.51

半岛bd体育手机客户端 性质

质量水平	200
测定	≥99%
形式	powder
溶解性	warm ethanol: 10 mg/mL, clear to slightly hazy, colorless to faintly yellow
储存温度	2-8℃
SMILES string	O=C(Nc1ncnc2nc[nH]c12)c3ccccc3
InChI	1S/C12H9N5O/c18-12(8-4-2-1-3-5-8)17-11-9-10(14-6-13-9)15-7-16-11/h1-7H,(H2,13,14,15,16,17,18)
InChI key	QQJXZVKXNSFHRI-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H317 - H361d
预防措施声明	P201 - P202 - P280 - P301 + P312 - P302 + P352 - P308 + P313
危险分类	Acute Tox. 4 Oral - Repr. 2 - Skin Sens. 1
储存分类代码	11 - Combustible Solids
WGK	WGK 3
个人防护装备	dust mask type N95 (US), Eyeshields, Faceshields, Gloves