半岛bd体育手机客户端 说明
一般描述
CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular stresses, including short wavelength ultraviolet light (UVC), at the transcriptional and post-translational level. It acts as a translational activator. CIRBP can bind the 3′untranslated region of specific transcripts to stabilize them and facilitate their transport to ribosomes for translation. CIRBP affects NF-κB signaling as opposed to IL1B mRNA stability directly.
外形
Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 0.25 M Imidazole, 20% glycerol.
重悬
Detailed reconstitution instructions are sent along with the product
基本信息
NACRES | NA.32 |
半岛bd体育手机客户端 性质
生物来源 | human |
重组 | expressed inE. coli |
测定 | ≥90% (SDS-PAGE) |
形式 | lyophilized |
分子量 | 20.5 kDa |
包装 | pkg of 1 mg pkg of 20 μg |
杂质 | ≤1 EU/μg endotoxin (LAL test) |
UniProt登记号 | Q14011 |
运输 | wet ice |
储存温度 | ?70℃ |
Gene Information | human ... CIRBP(1153) |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H315 - H319 - H360D |
预防措施声明 | P201 - P280 - P305 + P351 + P338 - P308 + P313 - P337 + P313 |
危险分类 | Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 |
储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich