半岛bd体育手机客户端 说明
一般描述
(S)-(-)-Bay K8644, a dihydropyridine compound is a Ca2+channel activator. It is an enantiomer of Bay K 8644.
应用
(S)-(-)-Bay K8644 has been used as a
包装
1, 5 mg in glass bottle
生化/生理作用
(S)-(-)-Bay K8644 enhances Ca2+current, whereas the (+)-Bay K 8644 is a weak Ca2+channel antagonist. Bay K 8644 is lipophilic and it effectively scavenges superoxide anions.
特点和优势
This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
法律信息
Manufactured and sold with the permission of Bayer AG.
基本信息
经验(实验)分子式 | C16H15F3N2O4 |
分子量 | 356.30 |
MDL编号 | MFCD00153769 |
PubChem化学物质编号 | 24891582 |
NACRES | NA.77 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | solid |
颜色 | yellow |
溶解性 | H2O: slightly soluble ethanol: soluble (Organic solutions are stable for at least 20 days at RT.) |
储存温度 | 2-8℃ |
SMILES string | COC(=O)C1=C(C)NC(C)=C([C@H]1c2ccccc2C(F)(F)F)[N+]([O-])=O |
InChI | 1S/C16H15F3N2O4/c1-8-12(15(22)25-3)13(14(21(23)24)9(2)20-8)10-6-4-5-7-11(10)16(17,18)19/h4-7,13,20H,1-3H3/t13-/m0/s1 |
InChI key | ZFLWDHHVRRZMEI-ZDUSSCGKSA-N |
Gene Information | human ... ADORA3(140) rat ... Adora1(29290), Adora2a(25369) |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H315 - H319 |
预防措施声明 | P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313 |
危险分类 | Eye Irrit. 2 - Skin Irrit. 2 |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich