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(S)-(-)-Bay K8644

品牌
Sigma-Aldrich
CAS
98625-26-4
货号
B133
规格纯度
≥98% (HPLC), solid
价格
2684.1 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
98625-26-4
( S)-(-)-Bay K8644
S-(-)-1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid methyl ester
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

(S)-(-)-Bay K8644, a dihydropyridine compound is a Ca2+channel activator. It is an enantiomer of Bay K 8644.

应用

(S)-(-)-Bay K8644 has been used as a L -type calcium channel (LTCC) agonist in the suprachiasmatic nucleus (SCN) slices. It has also been used as a LTCC agonist to induce arrhythmia in rats.

包装

1, 5 mg in glass bottle

生化/生理作用

(S)-(-)-Bay K8644 enhances Ca2+current, whereas the (+)-Bay K 8644 is a weak Ca2+channel antagonist. Bay K 8644 is lipophilic and it effectively scavenges superoxide anions.

特点和优势

This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

法律信息

Manufactured and sold with the permission of Bayer AG.

基本信息

经验(实验)分子式 C16H15F3N2O4
分子量 356.30
MDL编号 MFCD00153769
PubChem化学物质编号 24891582
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 solid
颜色 yellow
溶解性 H2O: slightly soluble
ethanol: soluble (Organic solutions are stable for at least 20 days at RT.)
储存温度 2-8℃
SMILES string COC(=O)C1=C(C)NC(C)=C([C@H]1c2ccccc2C(F)(F)F)[N+]([O-])=O
InChI 1S/C16H15F3N2O4/c1-8-12(15(22)25-3)13(14(21(23)24)9(2)20-8)10-6-4-5-7-11(10)16(17,18)19/h4-7,13,20H,1-3H3/t13-/m0/s1
InChI key ZFLWDHHVRRZMEI-ZDUSSCGKSA-N
Gene Information human ... ADORA3(140)
rat ... Adora1(29290), Adora2a(25369)

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H315 - H319
预防措施声明 P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
危险分类 Eye Irrit. 2 - Skin Irrit. 2
储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 dust mask type N95 (US), Eyeshields, Gloves

Sigma-Aldrich

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