半岛bd体育手机客户端 说明

一般描述

Caseins constitute 80% of the total milk proteins in the cow. κ-Casein is one of the major allergens in cow milk. It is a glycosylated protein comprising galactose, galactosamine, and sialic acid. It exists as tri- or tetrasaccharides and occurs in different isoforms based on the number of oligosaccharides attached to it. κ-Casein has a hydrophobic N-terminus and a hydrophilic C-terminus region.

应用

κ-Casein from bovine milk has been used:

• as a standard to quantify the casein concentration and to evaluate the ability of the bacterial strain to hydrolyze caseins released by HM Mozzarella
• in LPS-depleted cow′s milk protein preparation for lymphoproliferation assay
• as standard to quantify κ-casein concentration in skimmed milk samples by reversed-phase high-performance liquid chromatography (RP-HPLC)

包装

100, 250 mg in poly bottle
1 g in poly bottle

生化/生理作用

κ-Casein from bovine milk is an immunoglobulin E (IgE)-binding epitope belonging to the casein phosphoprotein family. κ-Casein is important to the electrostatic and steric stabilization of casein micelles suspensions. It resists calcium precipitation and therefore, stabilizes other caseins. κ-Casein has been a target of research for creating low-phenylalanine milk through gene modification, which is important for patients suffering from metabolic diseases such as phenylketonuria (PKU).

基本信息

EC 号	232-555-1
MDL编号	MFCD00081481
NACRES	NA.61

半岛bd体育手机客户端 性质

质量水平	200
生物来源	bovine milk
测定	≥70% (PAGE)
形式	lyophilized powder
technique(s)	isoelectric focusing (IEF): suitable
储存温度	?20℃
Gene Information	cow ... MKCAS(100531419), MKCASP(105755569)

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 1
个人防护装备	Eyeshields, Gloves, type N95 (US)