1,8-Dihydroxy-3-methylanthraquinone

半岛bd体育手机客户端 说明

应用

Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells . It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae)in vitro.

包装

50 mg in glass insert
1 g in glass bottle

生化/生理作用

Anticancer activity for chrysophanic acid is via the EGFR/mTOR mediated signaling transduction pathway . Chrysophanic acid has two hydrophobic positions on the molecule (C-6 and the methyl group attached to C-3) which are responsible for the compound′s activity against poliovirus .

其他说明

Keep container tightly closed in a dry and well-ventilated place.

基本信息

经验(实验)分子式	C15H10O4
分子量	254.24
Beilstein	1252300
EC 号	207-572-2
MDL编号	MFCD00001208
PubChem化学物质编号	57648009
NACRES	NA.85

半岛bd体育手机客户端 性质

质量水平	100
测定	98%
形式	crystalline
颜色	yellow-orange
溶解性	chloroform: 1%
作用机制	enzyme | inhibits
抗生素抗菌谱	neoplastics viruses
SMILES string	Cc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1
InChI	1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3
InChI key	LQGUBLBATBMXHT-UHFFFAOYSA-N
Gene Information	human ... ELA2(1991)

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves