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位置: 首页> 品牌> Sigma-Aldrich> 活化7-脱氢胆固醇

Cholecalciferol

胆钙化醇

品牌
Sigma-Aldrich
CAS
67-97-0
货号
C9774
规格纯度
analytical standard
价格
1189.47 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
67-97-0
Cholecalciferol
Calciol
(+)-Vitamin D 3
7-Dehydrocholesterol activated
Activated 7-dehydrocholesterol
胆钙化醇
活化7-脱氢胆固醇
(+)-维生素 D 3
胆骨化醇
活化7-脱氢胆甾醇
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Cholecalciferol, also called vitamin D3, promotes the absorption of calcium and phosphorus in the body to regulate bone growth. It is most commonly found in humans and animals and is produced in our skin when exposed to sunlight. It is used to treat and prevent bone disorders (such as rickets, osteomalacia).

应用

Cholecalciferol has been used as an internal standard in high-performance liquid chromatography (HPLC) to analyze serum vitamin D levels. It has also been used as a standard in liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) to quantify vitamin D 3 in sunflower oil.
Cholecalciferol may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography.

包装

1, 5 amp in ampule
Packaged in flame-sealed ampules under Argon

生化/生理作用

维生素 D 借以发挥作用的受体是配体依赖性转录因子超家族的成员。调控正常细胞和癌细胞的增殖和分化。对乳腺癌、结肠癌和前列腺癌细胞具有抗增殖和抗转移作用。肠和骨骼中的活化维生素 D 受体维持着钙的吸收和平衡。
Cholecalciferol is sourced either through the diet or exposing skin to ultraviolet rays. Oral administration of vitamin D 3 is readily absorbed and is stored in adipose tissue. Deficiency of vitamin D is often observed in chronic kidney disease.

基本信息

经验(实验)分子式 C27H44O
分子量 384.64
Beilstein 2339331
EC 号 200-673-2
MDL编号 MFCD00078131
eCl@ss 34058003
PubChem化学物质编号 24893197
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 200
生物来源 synthetic (organic - wool)
等级 analytical standard
测定 ≥97.0%
形式 crystalline
包装 pkg of 250 mg
颜色 white
mp 83-86 ℃ (lit.)
储存温度 2-8℃
SMILES string CC(C)CCC[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C
InChI 1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1
InChI key QYSXJUFSXHHAJI-YRZJJWOYSA-N
Gene Information human ... VDR(7421)

安全信息

象形图 GHS06GHS08
警示用语: Danger
危险声明 H300 + H310 + H330 - H372
预防措施声明 P260 - P262 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P314
危险分类 Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - STOT RE 1 Oral
储存分类代码 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

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