半岛bd体育手机客户端 说明

一般描述

4-Methylpyrazole inhibits CYP2E1 activity. It also acts as alcohol dehydrogenase inhibitor.

应用

Fomepizole (4-Methylpyrazole) can be used as:

• A reactant to prepare 4-methyl-1-phenyl-1H-pyrazole by reacting with bromobenzene viaN-arylation using a copper catalyst.
• A starting material for the synthesis of 4-methyl-3(5)-nitropyrazole by nitration.
• A ligand in the preparation of gallium(III) complex of 4-methylpyrazole as potential antitumor and antiviral agent.

甲醇和乙二醇中毒的有效解毒剂。

包装

1, 5 g in glass bottle

生化/生理作用

Alcohol dehydrogenase inhibitor.
醇脱氢酶抑制剂

基本信息

经验(实验)分子式	C4H6N2
分子量	82.10
Beilstein	105204
EC 号	231-445-0
MDL编号	MFCD00005245
PubChem化学物质编号	24853343
NACRES	NA.22

半岛bd体育手机客户端 性质

测定	99%
折射率	n 20/D 1.495 (lit.)
bp	99-100 ℃/6 mmHg (lit.)
溶解性	alcohol: soluble(lit.) water: soluble(lit.)
密度	0.993 g/mL at 25 ℃ (lit.)
SMILES string	Cc1cn[nH]c1
InChI	1S/C4H6N2/c1-4-2-5-6-3-4/h2-3H,1H3,(H,5,6)
InChI key	RIKMMFOAQPJVMX-UHFFFAOYSA-N
Gene Information	human ... ADH1A(124), ADH1B(125), ADH1C(126)

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H315 - H319 - H335
预防措施声明	P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类	Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	10 - Combustible liquids
WGK	WGK 3
闪点(F)	204.8 °F - closed cup
闪点(C)	96 ℃ - closed cup
个人防护装备	Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter