半岛bd体育手机客户端 说明

一般描述

Norvaline is a non-proteinogenic α-amino acid and is also called DL -α-aminovaleric acid. It is produced in Gram-negative microorganisms includingEscherichia coliand is also a part of the antifungal peptide produced byBacillus subtilis.

应用

DL -Norvaline has been used as an internal standard:

• to analyze metabolites in cultured mammalian cells by gas chromatography-mass spectrometry (GC-MS)
• to convert cysteine and cystine to Cys MPA (S-2-carboxyethylthio- L -cysteine) and quantify the same using a high-performance liquid chromatography (HPLC) analyzer
• for free amino acid analysis in samples of oocytes by liquid chromatography

包装

25, 100 g in poly bottle

生化/生理作用

Norvaline mediates physiological and pathophysiological processes promoting nitric oxide production. It is used to treat Alzheimer′s disease and is effective against artificial metabolic syndrome in rats. Norvaline exhibits phase transition upon cooling below 190 K and hence it is useful in molecular machines. DL -Norvaline serves as a prototype for research in polymorphism and molecular dynamics of aliphatic α-amino acids containing linear side-chain. It influences the activity, stability, and side-chain packaging of proteins.
DL-戊氨酸是一种神经递质。

基本信息

线性分子式	CH3CH2CH2CH(NH2)COOH
分子量	117.15
Beilstein	1721163
EC 号	212-082-7
MDL编号	MFCD00064420
PubChem化学物质编号	24897829
NACRES	NA.26

半岛bd体育手机客户端 性质

测定	≥98% (TLC)
质量水平	200
形式	powder
technique(s)	HPLC: suitable
颜色	white
mp	>300 ℃
SMILES string	CCCC(N)C(O)=O
InChI	1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)
InChI key	SNDPXSYFESPGGJ-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)