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Prothionamide

品牌
Sigma-Aldrich
CAS
14222-60-7
货号
SMB00387
规格纯度
≥99% (HPLC)
价格
746.4 *本价格含增值税费
促销
服务
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  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
14222-60-7
Prothionamide
2-propylisonicotinylthioamide
2-Propylthioisonicotinamide
2-Propyl-4-pyridinecarbothioamide
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Prothionamide is an analogue of ethionamide, and is better tolerated and less toxic than ethionamide. It contains a propyl group instead of an ethyl group at the α position.
Chemical structure: pyridine

包装

1, 10 g in poly bottle

生化/生理作用

Prothionamide is the second line of drug used in leprosy and in tuberculosis. It is highly effective againstMycobacterium tuberculosis. In patients with multidrug-resistant tuberculosis (MDR-TB), prothionamide causes the development of hepatitis. In rare cases, it causes drug reaction with eosinophilia and systemic symptoms (DRESS) in patients with MDR-TB. DRESS is characterized by fever, hematologic abnormalities, skin eruption, and internal organ disruption.

其他说明

Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Non Combustible Solids

基本信息

经验(实验)分子式 C9H12N2S
分子量 180.27
MDL编号 MFCD00464119
PubChem化学物质编号 329824982
NACRES NA.85

半岛bd体育手机客户端 性质

质量水平 200
测定 ≥99% (HPLC)
形式 powder
储存条件 (Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510) Non Combustible liquids.)
颜色 yellow
作用机制 enzyme | interferes
抗生素抗菌谱 mycobacteria
储存温度 ?20℃
SMILES string NC(C1=CC(CCC)=NC=C1)=S
InChI 1S/C9H12N2S/c1-2-3-8-6-7(9(10)12)4-5-11-8/h4-6H,2-3H2,1H3,(H2,10,12)
InChI key VRDIULHPQTYCLN-UHFFFAOYSA-N

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H302
危险分类 Acute Tox. 4 Oral
储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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