半岛bd体育手机客户端 说明
生化/生理作用
M871 is a type 2-selective galanin receptor antagonist (GalR2/GalR1 Ki= 13.1/410 nM by competitive binding against 0.1 nM porcine galanin using membranes from CHO expressing respective human receptors; GalR2/GalR1 Ki= 2.5/1.1 nM in case of rat galanin) that potently blocks 10 nM rat galanin-induced inositol phosphate production in human GalR2-expressing CHO cells (by 100% with 0.1, 1 or 10 nM M871). M871 is widely employed in cultures (0.1 nM-2.5 μM) and in mice and ratsin vivovia ip., brain region- or other site-specific injections.
基本信息
| 经验(实验)分子式 | C108H163N27O28· xC2HF3O2 |
| 分子量 | 2287.61 (free base basis) |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥95% (HPLC) |
| 形式 | lyophilized powder |
| 颜色 | white to off-white |
| 储存温度 | ?20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
