GR 64349

半岛bd体育手机客户端 说明

Amino Acid Sequence

Lys-Asp-Ser-Phe-Val-Gly-R-γ-lactam-Leu-Met-NH2

一般描述

Neurokinin (NK) receptors are acted upon by tachykinins or neurokinins namely, NKA and NKB. These are endogenous ligands. An exogenous agonist/ligand for NK₂is GR 64349 peptide.

包装

1 mg in glass bottle

生化/生理作用

GR 64349 peptide acts as an agonist of neurokinin (NK₂) receptor, which leads to reduced NK₂response to kainate and AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), but not to NMDA (N-methyl-D-aspartate).

基本信息

经验(实验)分子式	C42H68N10O11S
分子量	921.11
PubChem化学物质编号	329799740
NACRES	NA.32

半岛bd体育手机客户端 性质

质量水平	200
测定	>96%
储存温度	?20℃
SMILES string	CSCC[C@H](NC(=O)[C@H](CC(C)C)N1CC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CCCCN)C(C)C)C1=O)C(N)=O
InChI	1S/C42H68N10O11S/c1-23(2)19-32(40(61)46-27(35(45)56)15-18-64-5)52-17-14-28(42(52)63)47-41(62)34(24(3)4)51-38(59)29(20-25-11-7-6-8-12-25)49-39(60)31(22-53)50-37(58)30(21-33(54)55)48-36(57)26(44)13-9-10-16-43/h6-8,11-12,23-24,26-32,34,53H,9-10,13-22,43-44H2,1-5H3,(H2,45,56)(H,46,61)(H,47,62)(H,48,57)(H,49,60)(H,50,58)(H,51,59)(H,54,55)/t26-,27-,28-,29-,30-,31-,32-,34-/m0/s1
InChI key	HVUNRXRFMQDMBO-NOJSRKIXSA-N
Gene Information	human ... TACR2(6865) mouse ... TACR2(21337) rat ... TACR2(25007)

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)