Cyrene^TM2-Methyltetrahydrofuran Blend

半岛bd体育手机客户端 说明

一般描述

Cyrene^?2-Methyltetrahydrofuran Blend with BHT as an inhibitor is specially formulated for use in automated processes and applications where lower viscosity is required, making it easier to handle while maintaining high yields.
This Cyrene^?blend is an alternative for NMP and DMF in many cross-coupling reactions. Neither Cyrene^?nor 2-Methyltetrahydrofuran have any genotoxic or mutagenic concerns associated with their use, making them much safer alternatives to traditional aprotic solvents.
This new blend is part of our Biorenewable product line, meaning that it is made from renewable resources and does not compete with food resources for its production, making it more environmentally sustainable for the future. The material has also been independently certified as 100% renewable carbon.

应用

This cosolvent solution has been shown to have similar reaction yields to NMP and DMF for many cross-coupling reactions, such as:

• HATU Amide Coupling - Replacement for DMF in amide and dipeptide coupling reactions (eq. 1)
• Suzuki-Miyaura coupling reaction (eq. 2)
• Sonogashira coupling reaction (eq. 3)

特点和优势

• Independently certified as 100% renewable carbon.
• Closer physical properties of NMP and DMF while maintaining high reaction yields.
• Sustainably produced and environmentally less hazardous than more traditional petroleum aprotic solvents
• Both Cyrene^?and 2-MeTHF are also much safer for handling without the genotoxic concerns of other solvents.
• It has a lower viscosity than neat Cyrene^?making it more optimized for automated processes. (See Table 2)

其他说明

To see other BioRenewable or Greener Solvents

法律信息

CYRENE is a trademark of Circa Group Pvt Ltd

基本信息

经验(实验)分子式	C6H8O3
分子量	128.13

半岛bd体育手机客户端 性质

形式	liquid
包含	30-80 ppm BHT as stabilizer
环保替代半岛bd体育手机客户端 特性	Safer Solvents and Auxiliaries Use of Renewable Feedstocks Learn more about the Principles of Green Chemistry.
密度	1.153 g/mL
环保替代半岛bd体育手机客户端 分类	Aligned

安全信息

象形图
警示用语：	Danger
危险声明	H225 - H315 - H318
预防措施声明	P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
危险分类	Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2
补充剂危害	EUH019
储存分类代码	3 - Flammable liquids
WGK	WGK 2