半岛bd体育手机客户端 说明
包装
1 mg in glass bottle
生化/生理作用
BVT.948 is a non-competitive inhibitor of protein tyrosine phosphatase (PTP). Enhances insulin signaling in cells and inhibits several cytochrome P450 isoformsin vitro.
特点和优势
BVT.948 is a non-competitive inhibitor of protein tyrosine phosphatase (PTP). Enhances insulin signaling in cells and inhibits several cytochrome P450 isoformsin vitro. Works through a different mechanism then the other PTP inhibitors. BVT.948 was able to enhance insulin signaling in cells, although it did not increase tyrosine phosphorylation globally. Furthermore, the compound was active in vivo,enhancing insulin tolerance tests in ob/ob mice, therefore apparently enhancing insulin sensitivity. BVT.948 was able to inhibit several other PTPs tested and also was efficient at inhibiting several cytochrome P450 isoformsin vitro.
基本信息
| 经验(实验)分子式 | C14H11NO3 |
| 分子量 | 241.24 |
| MDL编号 | MFCD00616487 |
| PubChem化学物质编号 | 24724422 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | solid |
| 储存条件 | desiccated protect from light under inert gas |
| 颜色 | red |
| 溶解性 | DMSO: 18 mg/mL H2O: insoluble |
| 储存温度 | ?20℃ |
| SMILES string | CC1(C)C(=O)N=C2c3ccccc3C(=O)C(O)=C12 |
| InChI | 1S/C14H11NO3/c1-14(2)9-10(15-13(14)18)7-5-3-4-6-8(7)11(16)12(9)17/h3-6,17H,1-2H3 |
| InChI key | BAQXWJQSUXZVIP-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H317 |
| 预防措施声明 | P280 |
| 危险分类 | Skin Sens. 1 |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
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