(2S)-OMPT

半岛bd体育手机客户端 说明

一般描述

OMPT is a selective agonist of the LPA3 receptor. It exhibits EC50 values of 68 nM and >6.8 μM for calcium mobilization in LPA3 and LPA2-expressing Sf9 cells, respectively. The (2S)-OMPT enantiomer is 5- to 20-fold more active than (2R)-OMPT in calcium release assays in both LPA3-transfected Sf9 and rat hepatoma Rh7777 cells.

应用

(2S)-OMPT may be used:

• to study its effects on lysophosphatidic acid receptor-3 (LPAR3) receptor
• to pre-incubate hepatocytes and also characterize the role of LPAR3 on insulin-cascade
• as an analog of LPA to study its effects on tube stability of 10T cells

包装

2 mL Amber Serum Vial with Stopper and Crimp Cap (857235P-500ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (857235P-1mg)

基本信息

经验(实验)分子式	C22H46NO6PS
分子量	483.64

半岛bd体育手机客户端 性质

测定	>99% (TLC)
形式	powder
包装	package of 1 × 1 mg ((857235P-1mg)) package of 1 × 500 μg ((857235P-500ug))
manufacturer/tradename	Avanti Polar Lipids 857235P
运输	dry ice
储存温度	?20℃
SMILES string	[H][C@](COP([O-])(O)=S)(OC)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	49.5 °F - closed cup
闪点(C)	9.7 ℃ - closed cup