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位置: 首页> 品牌> Sigma-Aldrich> Ac-rCEHfRWC-NH2, TFA (D-amino acids in lower case; C2→C8 disulfide)

LY2112688 trifluoroacetate

品牌
Sigma-Aldrich
CAS
819048-44-7
货号
SML2949
规格纯度
≥95% (HPLC)
价格
1055.93 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
819048-44-7
LY2112688 trifluoroacetate
LY-2112688 TFA salt
Ac-D-Arg-c(Cys-Glu-His-D-Phe-Arg-Trp-Cys)-NH2, trifluoroacetate salt
Ac-D-Arg-cyclo[Cys-Glu-His-D-Phe-Arg-Trp-Cys]-NH2, trifluoroacetate salt
Ac-rCEHfRWC-NH 2, TFA (D-amino acids in lower case; C2→C8 disulfide)
Acetyl-D-Arg-Cys-Glu-His-D-Phe-Arg-Trp-Cys-NH2, trifluoroacetate salt (Cys2→Cys8 disulfide)
LY 2112688 TFA salt
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

生化/生理作用

LY2112688 is a beta-melanocyte-stimulating hormone (β-MSH)-derived peptide that acts as a high-affinity, potent and selective melanocortin receptor 4 (MC-4, MC-4R, MC4-R, MC4R) agonist (human/rat MC-4 Ki = 0.55/0.39 nM; human MC-1/3/5 Ki = 16.78/56.79/>500 nM). LY2112688 selectively induces MC-4-mediated cAMP release (MC-4/3 EC50 = 0.25 nM/1.61 nM, MC-4/3 Emax = 94.5%/84.1% of NDP-α-MSH Emax using HEK293 expressing respective human receptors) and exhibitsin vivoefficacy in reducing daily food intake and promoting weight loss among diet-induced obese rats (75 & 299 nmol/kg/day s.c.).

基本信息

经验(实验)分子式 C51H70N18O11S2· xC2HF3O2
分子量 1175.35 (free base basis)

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥95% (HPLC)
形式 lyophilized powder
颜色 white to off-white
储存温度 ?20℃

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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