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位置: 首页> 品牌> Sigma-Aldrich> JNJ-10198409

JNJ-10198409

品牌
Sigma-Aldrich
CAS
627518-40-5
货号
J4649
规格纯度
≥98% (HPLC), solid
价格
2255.27 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
627518-40-5
JNJ-10198409
3-Fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine
N-(3-fluorophenyl)-2,4-dihydro-6,7-dimethoxy-Indeno[1,2-c]pyrazol-3-amine
RWJ 540973
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

包装

1, 5 mg in glass bottle

生化/生理作用

JNJ-10198409 is a potent ATP-competitive inhibitor of Platelet-Derived Growth Factor receptor tyrosine kinase (PDGF-RTK) with both antiangiogenicand a directtumor cell antiproliferative activity. It is selective for PDGF-β kinase with IC50values of 4.2 nM for PDGF-β and 45 nM for PDGF-α kinase.

特点和优势

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
This compound is featured on the PAF Receptor and PDGFR pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式 C18H16FN3O2
分子量 325.34
PubChem化学物质编号 329815736
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 solid
颜色 off-white
溶解性 DMSO: >10 mg/mL
H2O: <2 mg/mL
创始人 Johnson & Johnson
储存温度 ?20℃
SMILES string COc1cc2Cc3c(Nc4cccc(F)c4)n[nH]c3-c2cc1OC
InChI 1S/C18H16FN3O2/c1-23-15-7-10-6-14-17(13(10)9-16(15)24-2)21-22-18(14)20-12-5-3-4-11(19)8-12/h3-5,7-9H,6H2,1-2H3,(H2,20,21,22)
InChI key ZDNURMVOKAERHZ-UHFFFAOYSA-N

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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