半岛bd体育手机客户端 说明
一般描述
Non-reducing disaccharide which yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation bothin vivoandin vitro. Oral administration of trehalose has been shown to effectively extend lifespan in a murine Huntington disease model. Also known to accumulate in osmotically-stressed cultured bacterial cells and protect against the adverse effects of dehydration.
Non-reducing disaccharide that yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation bothin vivoandin vitro. Oral administration of trehalose has been shown to effectively extend lifespan in a murine Huntington disease model. Also known to accumulate in osmotically-stressed cultured bacterial cells and protect against the adverse effects of dehydration. Reported to prevent myoglobin collapse and preserve its internal mobility.
包装
50 g in Glass bottle
1 kg in Glass bottle
警告
Toxicity: Standard Handling (A)
其他说明
Sarkar, S., et al. 2007.J. Biol. Chem.In press.
Tanaka, M., et al. 2004.Nat. Med.10,148.
Sastry, G.M. and Agmon, N. 1997.Biochemistry36,7097.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C12H22O11· 2H2O |
分子量 | 378.33 |
MDL编号 | MFCD00071594 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥97.5% (by Assay) |
形式 | solid |
manufacturer/tradename | Calbiochem? |
储存条件 | OK to freeze |
溶解性 | water: 100 mg/mL |
痕量阳离子 | Fe: <5 ppm heavy metals: <10 ppm |
运输 | ambient |
储存温度 | 15-25℃ |
InChI | 1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1 |
InChI key | DPVHGFAJLZWDOC-PVXXTIHASA-N |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich