半岛bd体育手机客户端 说明
生化/生理作用
Rp-8-bromo-cGMPS is a cell permeable cGMP analog that blocks cGMP-dependent protein kinase (cGK, G-kinase, Protein Kinase G, PKG). Rp-8-bromo-cGMPS is resistant to hydrolysis by phosphodiesterases and binds cGK without activating it, resulting in competitive inhibition.
基本信息
经验(实验)分子式 | C10H10BrN5O6PS · Na |
分子量 | 462.15 |
MDL编号 | MFCD04037242 |
PubChem化学物质编号 | 329825500 |
NACRES | NA.77 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | lyophilized solid |
颜色 | white to beige |
储存温度 | ?20℃ |
SMILES string | O=C1C2=C(N([C@@H]3O[C@H](CO[P@@](O4)([O-])=S)[C@@H]4[C@H]3O)C(Br)=N2)N=C(N)N1.[Na+] |
InChI | 1S/C10H11BrN5O6PS.Na/c11-9-13-3-6(14-10(12)15-7(3)18)16(9)8-4(17)5-2(21-8)1-20-23(19,24)22-5;/h2,4-5,8,17H,1H2,(H,19,24)(H3,12,14,15,18);/q;+1/p-1/t2-,4-,5-,8-,23-;/m1./s1 |
InChI key | CHTSSROWUAICIL-GMKUFTCMSA-M |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich