半岛bd体育手机客户端 说明
一般描述
A reversible and ATP-competitive inhibitor of protein kinase C (Ki= 10 nM). Inhibits protein kinase A at much higher concentrations (Ki= 2 ?M). An enhanced water soluble form of Bisindolylmaleimide I (Cat. No. 203290).
An enhanced water-soluble form of Bisindolylmaleimide I (Cat. No. 203290). A reversible and ATP-competitive inhibitor of protein kinase C (Ki= 10 nM). May inhibit protein kinase A at much higher concentrations (Ki= 2 ?M).
包装
1 mg in Plastic ampoule
250 μg in Plastic ampoule
生化/生理作用
Target Ki: 10 nM against protein kinase C
Primary Target
Protein kinase C
Product competes with ATP.
Cell permeable: no
Reversible: yes
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.
其他说明
Le Panse, R., et al. 1994.Mol. Pharmacol.46,445.
Kuchera, S., et al. 1993.Agents Actions39,C169.
Wilkinson, S.E., et al. 1993.Biochem. J.294,335.
Toullec, D., et al. 1991.J. Biol. Chem.266,15771.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C25H24N4O2· xHCl |
| 分子量 | 412.48 (free base basis) |
| MDL编号 | MFCD00236429 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥95% (HPLC) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem? |
| 储存条件 | OK to freeze |
| 颜色 | orange-red |
| 溶解性 | water: 10 mg/mL DMSO: 20 mg/mL |
| 运输 | ambient |
| 储存温度 | 2-8℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
