半岛bd体育手机客户端 说明

一般描述

Conjugated addition of secondary amines, imidazole and pyrazole to methyl 2 methyl 2-acetamidoacrylate in the presence of a catalyst results in the formation of β-Dialkylamino-α-alanine and β-(N-heteroaryl)-α-alanine derivatives. Methyl-2-acetamidoacrylate (M2AA) is an anti-inflammatory agent. The catalytic reaction of methyl 2-acetamidoacrylate with Grignard′s reagents affords α-amino esters. M2AA can form thermosensitive copolymers with methyl acrylate.
Methyl ester of 2-acetamidoacrylate . methyl 2-acetamidoacrylate (Me-2-AA) is a di-unsaturated α-amino acid derivative. methyl-2-acetamidoacrylate exihibits anti -inflammatory properties, it is very effective against lipopolysaccharide (LPS)- induced nitric oxide production by RAW 264.

应用

Methyl 2-acetamidoacrylate can undergo [2+2] cycloaddition (Michael–Dieckmann-type reaction) with ketene diethyl acetal to yield the cyclobutane core. It may be used in rhodium-catalyzed 2-alkenylpyrrole formation.

包装

1, 5 g in glass bottle

基本信息

线性分子式	H2C=C(NHCOCH3)CO2CH3
分子量	143.14
MDL编号	MFCD00013394
PubChem化学物质编号	24859082

半岛bd体育手机客户端 性质

质量水平	100
测定	98%
bp	104 ℃/8 mmHg (lit.)
mp	50-52 ℃ (lit.)
SMILES string	COC(=O)C(=C)NC(C)=O
InChI	1S/C6H9NO3/c1-4(6(9)10-3)7-5(2)8/h1H2,2-3H3,(H,7,8)
InChI key	SMWNFFKPVLVOQQ-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	235.4 °F - closed cup
闪点(C)	113 ℃ - closed cup
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves