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位置: 首页> 品牌> Sigma-Aldrich> 4′-去甲基表鬼臼毒素 -(4,6-O-亚乙基-β- D -吡喃葡萄糖苷)

Etoposide

4′-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-β- D -glucopyranoside)

CAS
33419-42-0
货号
E2600000
规格纯度
European Pharmacopoeia (EP) Reference Standard
价格
1572.27 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
33419-42-0
Etoposide
VP-16-213
4′-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-β- D -glucopyranoside)
依托泊苷
4′-去甲基表鬼臼毒素 -(4,6-O-亚乙基-β- D -吡喃葡萄糖苷)
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

依托泊甙是一种抗肿瘤试剂,和拓扑异构酶II和DNA结合,增强DNA双链和单链剪切和可逆抑制解除。 在S期和G2期阻止细胞周期;诱导正常和肿瘤细胞系凋亡;抑制癌蛋白Mdm2的合成,引起Mdm2过量表达的肿瘤系细胞凋亡。

包装

Unit quantity: 150 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式 C29H32O13
分子量 588.56
MDL编号 MFCD00869325
PubChem化学物质编号 329799033
NACRES NA.24

半岛bd体育手机客户端 性质

等级 pharmaceutical primary standard
manufacturer/tradename EDQM
application(s) pharmaceutical (small molecule)
格式 neat
储存温度 2-8℃
SMILES string COc1cc(cc(OC)c1O)[C@H]2[C@@H]3[C@H](COC3=O)[C@H](O[C@@H]4O[C@@H]5CO[C@@H](C)O[C@H]5[C@H](O)[C@H]4O)c6cc7OCOc7cc26
InChI 1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1
InChI key VJJPUSNTGOMMGY-MRVIYFEKSA-N
Gene Information human ... TOP2A(7153), TOP2B(7155)

安全信息

象形图 GHS07GHS08
警示用语: Danger
危险声明 H302 - H350 - H361d - H412
预防措施声明 P201 - P280 - P301 + P312 + P330 - P308 + P313
危险分类 Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 1B - Repr. 2
储存分类代码 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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