Difluoromethyl Phenyl Sulfone

半岛bd体育手机客户端 说明

应用

Reagent Used for

• Reductive silylation and the preparation of trifluoro- and difluoromethylsilanes by reductive coupling of fluoromethyl sulfones, sulfoxides and sulfides with chlorosilanes
• Fluoroalkylation/chloroalkylation of α,β-enones, arynes, acetylenic ketones and other Michael acceptors
• Difluoromethylation of primary alkyl halides via nucleophilic substitution-reductive desulfonylation

Reagent used in Preparation of

• α-difluoromethyl amines via stereoselective (phenylsulfonyl)difluoromethylation of chiral sulfinyl aldimines
• Anti-difluoropropanediols via potassium tert-butoxide-catalyzed difluoromethylenation of aldehydes
• β-difluoromethylated and β-difluoromethylenated alcohols and amines by regioselective nucleophilic difluoromethylation of 1,2-cyclic sulfates and sulfamidates
• Difluoroalkenes from alkyl halides via nucleophilic substitution-elimination
• Difluoromethyl alcohol derivatives from enolizable and non-enolizable carbonyl compounds using nucleophilic phenylsulfonyldifluoromethylation-reductive desulfonylation strategy
• Fluoromethylated vicinal ethylenediamines via fluoromethylation of chiral α-aminobutanesulfinimines with (phenylsulfonyl)fluoromethanes followed by reductive desulfonylation and alcoholysis

基本信息

经验(实验)分子式	C7H6F2O2S
分子量	192.18
Beilstein	2259218
MDL编号	MFCD01050170
PubChem化学物质编号	329765583
NACRES	NA.22

半岛bd体育手机客户端 性质

质量水平	100
测定	≥97%
SMILES string	FC(F)S(=O)(=O)c1ccccc1
InChI	1S/C7H6F2O2S/c8-7(9)12(10,11)6-4-2-1-3-5-6/h1-5,7H
InChI key	LRHDNAVPELLXDL-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319
预防措施声明	P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2
储存分类代码	10 - Combustible liquids
WGK	WGK 3
闪点(F)	264.0 °F
闪点(C)	128.9 ℃