半岛bd体育手机客户端 说明
一般描述
Diacerein is known to be a suitable drug to treat osteoarthritis and prevent vascular diseases. It is a semi-synthetic anthraquinone derivative which acts by inhibiting the production of interleukin-1 and secretion of metalloproteases.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
生化/生理作用
复方泻药/泻药；通过释放内源性乙酰胆碱来增加肠道平滑肌的收缩。抗肿瘤活性与活性氧簇 (ROS) 产生增加相关，活性氧簇反过来降低线粒体跨膜电位，从而诱导渗透性转换，启动一系列事件，最终导致细胞凋亡。遗传毒性和致突变性似乎是由于芦荟大黄素抑制了拓扑异构酶II的活性。
包装
Unit quantity: 20 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
注意
Please find SDS provided by EDQM here..
其他说明
Sales restrictions may apply.
基本信息
| 经验(实验)分子式 | C15H10O5 |
| 分子量 | 270.24 |
| Beilstein | 2059062 |
| MDL编号 | MFCD00017373 |
| PubChem化学物质编号 | 329831502 |
| NACRES | NA.24 |
半岛bd体育手机客户端 性质
| 生物来源 | synthetic |
| 等级 | pharmaceutical primary standard |
| agency | EP |
| 形式 | solid |
| manufacturer/tradename | EDQM |
| technique(s) | gas chromatography (GC): suitable liquid chromatography (LC): suitable |
| application(s) | pharmaceutical (small molecule) |
| 格式 | neat |
| 储存温度 | 2-8℃ |
| SMILES string | OCc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1 |
| InChI | 1S/C15H10O5/c16-6-7-4-9-13(11(18)5-7)15(20)12-8(14(9)19)2-1-3-10(12)17/h1-5,16-18H,6H2 |
| InChI key | YDQWDHRMZQUTBA-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 |
| 预防措施声明 | P301 + P312 + P330 |
| 危险分类 | Acute Tox. 4 Oral |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
