半岛bd体育手机客户端 说明
应用
This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and Boc-protected amino group at the other, which can be deprotected with mildly acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. BocNH-PEG5-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC?molecules) for targeted protein degradation.
法律信息
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
基本信息
经验(实验)分子式 | C17H33NO9 |
分子量 | 395.45 |
半岛bd体育手机客户端 性质
形式 | liquid |
reaction suitability | reaction type: Pegylations reagent type: cross-linking reagent |
储存温度 | ?20℃ |
SMILES string | OC(COCCOCCOCCOCCOCCNC(OC(C)(C)C)=O)=O OC(COCCOCCOCCOCCOCCNC(OC(C)(C)C)=O)=O |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich