半岛bd体育手机客户端 说明

一般描述

2-Chloro-2,2-difluoroacetophenone is a difluorocarbene reagent, which is generally used in the synthesis of 2,2-difluoro enol silyl ethers, andgem-difluoromethene derived compounds.

应用

2-Chloro-2,2-difluoroacetophenone can be used:

• As a reagent in the difluoromethylation of various phenols to yield aryl difluoromethyl ethers.
• As a precursor in the Baylis-Hillman reaction of fluoroalkyl ketones to obtain chlorodifluoromethyl containing products.
• As a substrate in the synthesis of propargyl alcohols using a novel ruthenium catalyst.

Reagent is an effective product for the synthesis of difluoromethylated phenols in the presence of mild base and aqueous solvent.

包装

1, 10 g in glass bottle

基本信息

线性分子式	C6H5COCF2Cl
分子量	190.57
Beilstein	2251448
MDL编号	MFCD00042123
PubChem化学物质编号	329768330

半岛bd体育手机客户端 性质

质量水平	100
测定	95%
折射率	n 20/D 1.4954 n 20/D 1.497 (lit.)
bp	94-96 ℃/35 mmHg (lit.)
密度	1.293 g/mL at 25 ℃ (lit.) 1.3178 g/mL at 25 ℃
SMILES string	FC(F)(Cl)C(=O)c1ccccc1
InChI	1S/C8H5ClF2O/c9-8(10,11)7(12)6-4-2-1-3-5-6/h1-5H
InChI key	MNOONJNILVDLSW-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	10 - Combustible liquids
WGK	WGK 3
闪点(F)	160.0 °F
闪点(C)	71.1 ℃