Fmoc-N-Me-Cys(Trt)-OH

半岛bd体育手机客户端 说明

应用

Fmoc-N-Me-Cys(Trt)-OH is a Fmoc-protected derivative ofN-methyl cysteine used as a building block to prepare peptide thioesters under acidic conditions. The residue attached to the amino group ofN-methylcysteine can migrate to the cysteinyl thiol group, resulting in the formation of a peptide thioester. The introduction of this Fmoc-protected derivative is best achieved using HATU as a coupling reagent in the presence of DIPEA (N,N-Diisopropylethylamine).
It can also be used to prepare Fmoc-N-Me-Cys(Trt)-OAllyl intermediate for the solid-phase synthesis of dithiol Triostin A.

包装

1 g in glass bottle

基本信息

经验(实验)分子式	C38H33NO4S
分子量	599.74
NACRES	NA.26

半岛bd体育手机客户端 性质

质量水平	100
测定	97% (HPLC)
形式	powder or crystals
旋光性	[α]22/D -25.0°, c = 0.5% in dichloromethane
reaction suitability	reaction type: Fmoc solid-phase peptide synthesis
mp	234-239 ℃
application(s)	peptide synthesis
官能团	Fmoc
储存温度	2-8℃

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable