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位置: 首页> 品牌> Sigma-Aldrich> 还原型 β-烟酰胺腺嘌呤二核苷酸 二钠盐

β-Nicotinamide adenine dinucleotide, reduced disodium salt

还原型 β-烟酰胺腺嘌呤二核苷酸 二钠盐

品牌
Sigma-Aldrich
CAS
606-68-8
货号
N6660
规格纯度
~98%, pkg of 0.2 mg (per vial)
价格
1845.83 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
606-68-8
β-Nicotinamide adenine dinucleotide, reduced disodium salt
Coenzyme I reduced disodium salt
β-NADH
Diphosphopyridine nucleotide reduced disodium salt
β-DPNH
还原型 β-烟酰胺腺嘌呤二核苷酸 二钠盐
Diphosphopyridine nucleotide reduced 二钠盐
Coenzyme I reduced 二钠盐
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

β-Nicotinamide adenine dinucleotide (β-NAD) regulates energy metabolism and immunity. It is a cofactor for mitochondrial deacetylase sirtuin-3 enzyme and modulates inflammasome assembly. β-NAD supresses interleukin-1β levels in monocytic cells in inflammatory syndromes. β-NAD released by neurosecretory cells is a potential neurotransmitter. β-NAD is a vascular mediator in lung endothelial cells and may play a protective role against cytokine mediated inflammation.

应用

β-Nicotinamide adenine dinucleotide, reduced disodium salt has been used:

  • for the standard curve generation in neurotoxity assay of cortical neurons
  • in triosephosphate isomerase assay in jurkat JE6-1 cells
  • in lactate dehydrogenase assay

β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).

生化/生理作用

电子供体

重悬

溶液应新鲜制备并及时使用。

其他说明

根据 UV-Vis 测定的 NADH 含量包装。
这是 NADH 的常见形式;不要与 α 混淆-NADH。

基本信息

经验(实验)分子式 C21H27N7Na2O14P2
分子量 709.40
Beilstein 5230241
EC 号 210-123-3
MDL编号 MFCD00036200
PubChem化学物质编号 24897788
NACRES NA.51

半岛bd体育手机客户端 性质

质量水平 200
测定 ~98%
形式 powder
包装 pkg of 0.2 mg (per vial)
SMILES string [Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@H]2O[C@@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@H](O)[C@@H]2O
InChI 1S/C21H29N7O14P2.2Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33;;/h1,3-4,7-8,10-11,13-16,20-21,29-32H,2,5-6H2,(H2,23,33)(H,34,35)(H,36,37)(H2,22,24,25);;/q;2*+1/p-2/t10-,11+,13-,14+,15-,16+,20-,21+;;/m0../s1
InChI key QRGNQKGQENGQSE-QUWMEQBESA-L

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
个人防护装备 Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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