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位置: 首页> 品牌> Sigma-Aldrich> Wiskostatin-CAS 253449-04-6-Calbiochem

Wiskostatin-CAS 253449-04-6-Calbiochem

品牌
Sigma-Aldrich
CAS
253449-04-6
货号
681525
规格纯度
A cell-permeable N-alkylated carbazole derivative that selectively blocks actin filament assembly.
价格
1940.38 *本价格含增值税费
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半岛bd体育手机客户端 名称:
253449-04-6
Wiskostatin-CAS 253449-04-6-Calbiochem
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

A cell-permeable N-alkylated carbazole derivative that selectively blocks actin filament assembly. Acts as a selective, reversible inhibitor of N-WASP (neural Wiskott Aldrich syndrome protein), a signal integrating protein. Appears to bind to N-WASP, stabilize the autoinhibited conformation and prevent the activation of Arp2/3 (actin-related protein 2/3) complex.
A cell-permeable N-alkylated carbazole derivative that selectively blocks actin filament assembly. Acts as a selective, reversible inhibitor of neural Wiskott Aldrich Syndrome protein (N-WASP). Reported to bind to N-WASP, stabilize the auto-inhibited conformation, and prevent the activation of actin-related protein 2/3 (Arp2/3) complex.

包装

1, 5 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Cell permeable: yes
Primary Target
N-WASP (neural Wiskott Aldrich syndrome protein)
Product does not compete with ATP.
Reversible: yes

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Peterson, J.R., et al. 2004.Nat. Struct. Mol. Biol.11,747.
Peterson, J.R., and Mitchison, T.J. 2002.Chem. Biol.9,1275.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式 C17H18Br2N2O
分子量 426.15
MDL编号 MFCD00218393

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥95% (HPLC)
形式 solid
manufacturer/tradename Calbiochem?
储存条件 OK to freeze
protect from light
颜色 white
溶解性 DMSO: 5 mg/mL
运输 ambient
储存温度 ?20℃
InChI 1S/C17H18Br2N2O/c1-20(2)9-13(22)10-21-16-5-3-11(18)7-14(16)15-8-12(19)4-6-17(15)21/h3-8,13,22H,9-10H2,1-2H3
InChI key XUBJEDZHBUPBKL-UHFFFAOYSA-N

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3

Sigma-Aldrich

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